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вce журналы << Клиническая и экспериментальная тиреоидология << 2012 год << №3 <<
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РОЛЬ ТОНКОИГОЛЬНОЙ АСПИРАЦИОННОЙ БИОПСИИ В ДИНАМИЧЕСКОМ НАБЛЮДЕНИИ ПАЦИЕНТОВ С УЗЛОВЫМ ЗОБОМ

Г.В. Семкина, В.А. Смирнова, Ф.М. Абдулхабирова, В.Э.Ванушко
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Г.В. Семкина – аспирант ФГБУ Эндокринологический научный центр; В.А. Смирнова – аспирант кафедры эндокринологии Первого МГМУ им. И.М. Сеченова; Ф.М. Абдулхабирова – канд. мед. наук, ведущий научный сотрудник отделения терапии с группой патологии метаболизма и ожирения ФГБУ Эндокринологический научный центр
Адрес для корреспонденции: Ванушко Владимир Эдуардович – 117036, Москва, ул. Дмитрия Ульянова, д.11, ФГБУ Эндокринологический научный центр Минздравсоцразвития РФ. E-mail: vanushko@hotmail.com

Обзор литературы посвящен применению тонкоигольной аспирационной биопсии (ТАБ) в диагностике узловых образований щитовидной железы. Использование новой классификационной системы интерпретации результатов ТАБ позволяет значительно увеличить воспроизводимость данного метода и существенно сократить число ложноотрицательных результатов. Представлены современные данные об эпидемиологии узловых образований, новой системе интерпретации цитологических заключений ТАБ, проведена оценка роли ТАБ в динамическом наблюдении доброкачественных образований щитовидной железы.

Ключевые слова:
узловой зоб, тонкоигольная аспирационная биопсия, цитологическая оценка

Литература:
1. Баженова Е.А. Оптимизация диагностики раков щитовидной
железы 10 мм в наибольшем измерении: Автореф. дис. …
канд. мед. наук. Барнаул, 2004.
2. Белобородов В.А., Олифирова О.С., Шевченко С.П. и др. Морфологическая верификация рака щитовидной железы. Сиб. онкол. журн. 2007; 2: 70–72.
3. Ванушко В.Э., Кузнецов Н.С., Бельцевич Д.Г. и др. Прицельная
тонкоигольная пункционная биопсия в диагностике рака
щитовидной железы. Хирургия 2003; 10: 67–72.
4. Ванушко В.Э., Кузнецов Н.С., Гарбузов П.И., Фадеев В.В. Рак
щитовидной железы. Пробл. эндокринол. 2005; 4: 43–53.
5. Гринева Е.Н. Роль тонкоигольной аспирационной биопсии
в диагностике узловых образований щитовидной железы.
Пробл. эндокринол. 2005; 1: 10–15.
6. Дедов И.И. Клинические рекомендации Российской ассоциации эндокринологов по диагностике и лечению узлового зоба: Матер. 3го Всерос. тиреоидологич. конгр. М., 2004; 5—12.
7. Дедов И.И., Мельниченко Г.А., Фадеев В.В. и др. Клинические
рекомендации Российской ассоциации эндокринологов по
диагностике и лечению узлового зоба. Пробл. эндокринол.
2005; 5: 40–42.
8. Дедов И.И., Кузнецов Н.С., Мельниченко Г.А. и др. Эндокринная хирургия: “узкая” специальность или насущная необходимость? Клин. и экспер. тиреоидол. 2008; 1: 8–12.
9. Зайратьянц О.В. Эпидемиология и этиологическая структура
узлового зоба по данным аутопсий. Актуальные проблемы заболеваний щитовидной железы: Матер. 2го Всерос. тиреоидологич. конгр. М., 2002; 50–60.
10. Зубеев П.С., Потехина Ю.П., Коновалов В.А. Расширение возможностей тонкоигольной аспирационной биопсии под контролем УЗИ в диагностике узловых образований щитовидной
железы . Клин. тиреоидол. 2004; 3: 15–18.
11. Иванов Ю.В., Панченков Д.Н., Соловьев Н.А. и др. Роль пункционной тонкоигольной аспирационной биопсии в диагностике узловых образований щитовидной железы. Эндоскопич.
хир. 2010; 3: 25–34.
12. Коренев С.В., Плешков В.Г., Тугай В.В. Особенности дооперационной диагностики рака щитовидной железы. Рос. мед.
журн. 2005; 3: 13–16.
13. Митьков В.В. Практическое руководство по ультразвуковой
диагностике. М: Видар, 2006.
14. Непомнящая Е.М., Бирина Л.М., Рубцов В.Р. и др. Клиникоморфологические критерии прогноза рака щитовидной железы. Естественные науки 2004; 2: 95–97.
15. Орлинская Н.Ю., Саранцев Б.В. Особенности морфологической диагностики заболеваний щитовидной железы. Медицинский альманах 2011; 32: 172–174.
16. Тимофеева Н.И., Черников Р.И., Слепцов И.В. и др. Диагности
ческая ценность тонкоигольной аспирационной биопсии узлов щитовидной железы. Вестн. СанктПетербургского университета 2006; 11: 79–85.
17. Толстокоров А.С., Ершова Г.И., Коваленко Ю.В., Дергунова С.А.
Пункционные методы диагностики и лечения заболеваний
щитовидной железы. Саратовский науч.мед. журн. 2010; 2:
464–467.
18. Фадеев В.В., Ванушко В.Э. Комментарии к клиническим рекомендациям Американской ассоциации клинических эндокринологов и Европейской тиреоидологической ассоциации
по узловому зобу 2010 года . Клин. и экспер. тиреоидол. 2010;
3: 6–16.
19. Федотов Ю.Н., Воробьев С.Л., Черников Р.А. и др. Тонкоигольная аспирационная биопсия в диагностике заболеваний щитовидной железы. Корреляция между заключением цитолога
и гистолога, технические аспекты . Клин. и экспер. тиреоидол. 2009; 4: 28–33.
20. AACE/AME/ETA Thyroid Nodule Guidelines. Endocr. Pract.
2010; 16: 1–43.
21. AbdulJaber H.B., Lynn J. The surgical management of thyroid
cancer. Nucl. Med. Commun. 2004; 25: 869–872.
22. Abele J.S., Levine R.A. Diagnostic criteria and riskadapted
approach to indeterminate thyroid cytodiagnosis. Cancer Cytopathol. 2010; 118: 415–422.
23. Ali S.Z., Cibas E.S. The Bethesda System for Reporting Thyroid
Cytopathology: Definitions, Criteria and Explanatory Notes . New
York, Springer, 2009.
24. American Association of Clinical Endocrinologists and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules. Endocr.
Pract. 2006; 12: 63–103.
25. Baloch Z.W., Fleisher S., LiVolsi V.A. et al. Diagnosis of “follicular
neoplasm”: a gray zone in thyroid fineneedle aspiration cytology.
Diagn. Cytopathol. 2002; 26: 41–44.
26. Baloch Z.W., Livolsi V.A., Asa S.L. et al. Diagnostic terminology
and morphological criteria for cytologic diagnosis of thyroid
lesions: a synopsis of the National Cancer Institute thyroid fineneedle aspiration state of the science conference. Diagn.
Cytopathol. 2008; 36: 425–433.
27. Bartolazzi A., Gasbarri A., Papotti M. et al. The Thyroid Cancer
Study Group. Application of a immunodiagnostic method for
improving preoperative diagnosis of nodular thyroid lesions.
Lancet 2001; 357: 1644–1650.
28. Belfiore A., La Rosa G.L. Fineneedle aspiration biopsy of the thyroid . J. Endocrin. Met. Clin. North. Am. 2001; 30: 361–400.
29. BishopPitman M., Abele J., Ali S.Z. et al. Techniques for thyroid
FNA: a synopsis of the National Cancer Institute Thyroid Fine
Needle Aspiration State of the Science Conference. Diagn.
Cytopahol. 2008; 6: 407–424.
30. Boelaert K., Horacek J., Holder R.L. et al. Serum Thyrotropin
Concentration as a Novel Predictor of Malignancy in Thyroid
Nodules Investigated by FineNeedle Aspiration. J. Clin.
Endocrinol. Met. 2006; 91: 4295–4301.
31. British Thyroid Association, Royal College of Physicians: British
Thyroid Association Guidelines for the management of thyroid
cancer. 2nd edition. 2007 http:www.britishthyroid
association.org/Guidelines/
32. Caraci P., Aversa S., Mussa A. et al. Role of fineneedle aspiration
biopsy and frozensection evaluation in the surgical management
of thyroid nodules. Br. J. Surg. 2002; 89: 797–701.
33. Cesur M., Corapcioglu D., Bulut S. et al. Comparison of palpationguided fineneedle aspiration biopsy to ultrasoundguided fineneedle aspiration biopsy in the evaluation of thyroid nodules.
Thyroid 2006; 16; 555–561.
34. Chehade J.M., Silverberg A.B., Kim J. et al. Role of repeated fine
needle aspiration of thyroid nodules with benign cytologic featuresEndocr. Pract. 2001; 7: 237–243.
35. Chudova D., Wilde J.I., Wang E.T. et al. Molecular classification of
thyroid nodules using highdimensionality genomic data. J. Clin.
Endocrin. Metab. 2010; 95: 5296–5304.
36. Cibas E.S., Alexander E.K., Benson C.B. et al. Indications for
Thyroid FNA and PreFNA Requirements: A Synopsis of the
National Cancer Institute Thyroid FineNeedle Aspiration State
of the Science Conference. Diagn. Cytopathol. 2008; 36:
390–399.
37. Cibas E.S., Ali S.Z. The Bethesda System for Reporting Thyroid
Cytopathology. Am. J. Clin. Pathol. 2009; 132: 658–665.
38. Cibas E.S., Bibbo M. Thyroid FNA: Challenges and Opportunities.
Acta Cytologica 2011; 55: 489–491.
39. Cooper D.S., Doherty G.M., Haugen B.R. et al. Management
Guidelines for Patients with Thyroid Nodules and Differentiated
Thyroid Cancer. The American Thyroid Association Guidelines
Taskforce. Thyroid 2006; 16: 1–33.
40. Cramer H. Fine needle aspiration cytology of the thyroid: an
appraisal. Cancer Cytopathol. 2000; 90: 325–329.
41. Davidov T., Trooskin S.Z. et al. Routine secondopinion
cytopathology review of thyroid fine needle aspiration biopsies
reduces diagnostic thyroidectomy. Surgery 2010; 148: 1294–1301.
42. Deveci M.S., Deveci G., LiVolsi V.A. et al. Fineneedle aspiration of
follicular lesions of the thyroid: diagnosis and followup. Cytojournal 2006; 3: 9.
43. Duek S.D., Goldenberg D., Linn S. et al. The role of fineneedle aspiration and intraoperative frozen section in the surgical management of solitary thyroid nodules. Surg. Today 2002; 32: 857–861.
44. Eedes C.R., Wang H.H. Costeffectiveness of immediate specimen
adequacy assessment of thyroid fineneedle aspirations. Am. J.
Clin. Pathol. 2004; 121: 64–69.
45. Eng C.Y., Quraishi M.S., Bradley P.J. Meviaewnagement of
Thyroid nodules in adult patients. Head & Neck Oncology 2010; 2:
11–16.
46. Faquin W.C., Baloch Z.W. Fineneedle aspiration of follicular patterned lesions of the thyroid: diagnosis, management, and followup according to National Cancer Institute [NCI] recommendations. Diagn. Cytopathol. 2010; 38: 731–739.
47. Filie A.C., Asa S.L., Geisinger K.R. et al. Utilization of ancillary
studies in thyroid fine needle aspirates: a synopsis of the National
Cancer Institute Thyroid Fine Needle Aspiration State of the
Science Conference. Diagn. Cytopathol. 2008; 36: 438–441.
48. Flanagan M.B. et al. Repeat Thyroid Nodule FineNeedle Aspiration in Patients With Initial Benign Cytologic Results. Am. J.
Clin. Pathol. 2006; 125 (5): 698—702.
49. Frates M.C., Benson C.B., Charboneau J.W. et al. Management of
thyroid nodules detected at US: Society of Radiologists in
Ultrasound consensus conference statement. Radiology 2005; 237:
794–800.
50. Fusco A., Chiapetta G., Hui P. et al. Assessment of RET/PTC oncogene activation and clonality in thyroid nodules with incomplete
morphological evidence of papillary carcinoma. Am. J. Pathol.
2002; 160: 2157–2167.
51. French C.A., Alexander E.K., Cibas E.S. et al. Genetic and biological subgroups of lowstage follicular thyroid cancer. Am. J. Pathol.
2003; 162: 1053–1060.
52. Gabalec F., Cap J., Ryska A. et al. Benign fineneedle aspiration
cytology of thyroid nodule: to repeat or not to repeat? Eur. J.
Endocrinol. 2009; 161: 933–937.
53. Gharib H., Papini E. Thyroid nodules: Clinical importance, assessment, and treatment. Endocrin. Met. Clin. N. Am. 2007; 36:
707–735.
54. Giorgadze T., Rossi E.D., Fadda G. et al. Does the fine-needle aspiration diagnosis of “Hürthlecell neoplasm/follicular neoplasm
with oncocytic features” denote increased risk of malignancy?
Diagn. Cytopathol. 2004; 31: 307–312.
55. Haymart M.R., Repplinger D.J., Leverson G.E. et al. Higher Serum
Thyroid Stimulating Hormone Level in Thyroid Nodule Patients Is
Associated with Greater Risks of Differentiated Thyroid Cancer
and Advanced Tumor Stage. J. Clin. Endocrinol. Met. 2008; 93:
809–814.
56. Jo V.Y., Stelow E.B., Dustin S.M., Hanley K.Z. Malignancy risk for
fineneedle aspiration of thyroid lesions according to the Bethesda
System for Reporting Thyroid Cytopathology. Am. J. Clin. Pathol.
2010; 134: 450–456.
57. Jo V.Y., Van der Laan P.A., Marqusee E., Krane J.F. Repeatedly
Nondiagnostic Thyroid FineNeedle Aspirations Do Not Modify
Malignancy Risk. Acta Cytologica 2011; 55: 539–543.
58. Izquierdo R., Arekat M.R., Knudson P.E. et al. Comparison of palpationguided versus ultrasoundguided fineneedle aspiration
biopsies of thyroid nodules in an outpatient endocrinology prac
tice. Endocr. Pract. 2006; 12: 609–614.
59. Kelly N.P., Lim J.C., DeJong S. et al. Specimen adequacy and diagnostic specificity of ultrasoundguided fine needle aspirations of
nonpalpable thyroid nodules. Diagn. Cytopathol. 2006; 34:
188–190.
60. Khan I., Naz S., Akhter Z.M., Aziz N. Diagnostic accuracy of fine
needle aspiration of thyroid nodule versus biopsy in thyroid lesions.
J. Ayub. Med. Coll. Abbottabad. 2010; 22: 179–182.
61. Kim E.K., Park C.S., Chung W.Y. New et al. Sonographic Criteria
for Recommending FineNeedle Aspiration Biopsy of Non
palpable Solid Nodules of the Thyroid. Am. J. Roentgenol. 2002;
178: 687–691.
62. Kocjan G., CochandPriollet B., de Agustin P.P. et al. Diagnostic
terminology for reporting thyroid fine needle aspiration cytology:
European Federation of Cytology Societies thyroid working party
symposium, Lisbon 2009. Cytopathology 2010; 21: 86–92.
63. Koen T.M., Mody D.R., ScheiberPacht M. et al. Limiting the use of
atypical/inconclusive as a category in nongynecologic cytology
specimens. Arch. Pathol. Lab. Med. 2010; 134: 1016–1019.
64. Layfield L.J., Abrams J., CochandPriollet B. et al. Postthyroid
FNA testing and treatment options: a synopsis of the national cancer institute thyroid fine needle aspiration state of the science conference. Diagn. Cytopathol. 2008; 36: 442–448.
65. Layfield L.J., Morton M.J., Cramer H.M., Hirschowitz S. Implications of the proposed thyroid fineneedle aspiration category of
‘follicular lesion of undetermined significance’: a fiveyear multiinstitutional analysis. Diagn. Cytopathol. 2009; 37: 710–714.
66. Layfield L.J., Cibas E.S., Baloch Z. Thyroid fine needle aspiration
cytology: a review of the National Cancer Institute state of the science symposium. Cytopathology 2010; 21: 75–85.
67. Lee Y.H., Kim D.W., In H.S. et al. Differentiation between Benign
and Malignant Solid Thyroid Nodules Using an US Classification
System. Korean J. Radiol. 2011; 12: 559–567.
68. Ljung E.B., Langer J., Mazzaferri E.L. et al. Training, credentialing
and recredentialing for the performanceperformance of a thyroid
FNA: a synopsis of the National Cancer Institute Thyroid Fine
Needle Aspiration State of the Science Conference. Diagn. Cytopathol. 2008; 36: 400–406.
69. Luu M.H., Fischer A.H., Pisharodi L., Owens C.L. Improved preoperative definitive diagnosis of papillary thyroid carcinoma in
FNAs prepared with both ThinPrep and conventional smears compared with FNAs prepared with ThinPrep alone. Cancer Cytopathol. 2011; 119: 68–73.
70. Luu M.H., Fischer A.H., Stockl T.J. et al. Atypical Follicular Cells
with Equivocal Features of Papillary Thyroid Carcinoma Is Not
a LowRisk Cytologic Diagnosis. Acta Cytologica 2011; 55:
526–530.
71. Marchevsky A.M., Walts A.E., Bose S. et al. Evidencebased evaluation of the risks of malignancy predicted by thyroid fine-needle
aspiration biopsies. Diagn. Cytopathol. 2010; 38: 252–259.
72. Melillo R.M., Santoro M., Vecchio G. Differential diagnosis of
thyroid nodules using fineneedle aspiration cytology and oncogene mutation screening: are we ready? F1000 Med. Rep.
2010; 2: 62.
73. Merchant S.H., Izquierdo R., Khurana K.K. Is repeated fineneedle
aspiration cytology useful in the management of patients with
benign nodular thyroid disease? Thyroid 2000; 10: 489–492.
74. Miccoli P., Minuto M.N., Galleri D. et al. Incidental thyroid carcinoma in a large series of consecutive patients operated on for
benign thyroid disease. ANZ J. Surg. 2006; 76: 123–126.
75. Moon W.J., Baek J.H., Jung S.L. et al. Ultrasonography and the
UltrasoundBased Management of Thyroid Nodules: Consensus
Statement and Recommendations. Korean J. Radiol. 2011;
12: 1–14.
76. Nasuti J.F., Gupta P.K., Baloch Z.W. Diagnostic value and cost
effectiveness of on site evaluation of fine needle aspiration specimens. Review of 5,688 cases. Diagn. Cytopathol. 2002; 27: 1–4.
77. Nayar R., Ivanovic M. The indeterminate thyroid fineneedle aspiration: experience from an academic center using terminology
similar to that proposed in the 2007 National Cancer Institute
Thyroid Fine Needle Aspiration State of the Science Conference.
Cancer Cytopathol. 2009; 117: 195–202.
78. NCI Thyroid Fine Needle Aspiration State of Science Conference.
Diagn. Cytopathol. 2008; 6: 388–448.
79. Ohori N.P., Nikiforova M.N., Schoedel K.E. et al. Contribution of
molecular testing to thyroid fineneedle aspiration cytology of ‘follicular lesion of undetermined significance/atypia of undetermined
significance’. Cancer Cytopathol. 2010; 118: 17–23.
80. Ohori N.P., Schoedel K.E. Variability in the Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Diagnosis in the Bethesda System for Reporting Thyroid
Cytopathology: Sources and Recommendations. Acta Cytologica
2011; 55: 492–498.
81. Olson M.T., Clark D.P., Erozan Y.S., Ali S.Z. Spectrum of Risk of
Malignancy in Subcategories of ‘Atypia of Undetermined Significance’. Acta Cytologica 2011; 5: 518–525.
82. Ono J.C., Wilbur D.C., Lee H. et al. Cytologic Features of Focal
Papillary Thyroid Carcinoma Arising within Follicular Adenoma:
A Masked Cytomorphologic Analysis of 17 Cases. Acta Cytologica
2011; 55: 531–538.
83. Orlandi A., Puscar A., Capriata E., Fideleff H. Repeated Fine-Needle Aspiration of the Thyroid in Benign Nodular Thyroid
Disease: Critical Evaluation of LongTerm FollowUp. Thyroid
2005; 15: 274–281.
84. Pu R.T., Yang J., Wasserman P.G. et al. Does Hurthle cell lesion/
neoplasm predict malignancy more than follicular lesion/neoplasm on thyroid fineneedle aspiration? Diagn. Cytopathol. 2006;
34: 330–334.
85. Redman R., Yoder B.J., Massoll N.A. Perceptions of diagnostic terminology and cytopathologic reporting of fineneedle aspiration
biopsies of thyroid nodules: a survey of clinicians and pathologists.
Thyroid 2006; 16: 1003–1008.
86. Reiners C., Wegscheider K., Schicha H. et al. Prevalence of thyroid
disorders in the working population of Germany: ultrasonography
screening in 96,278 unselected employees. Thyroid 2004; 14:
926–932.
87. Renshaw A.A. Should ‘atypical follicular cells’ in thyroid fine-needle aspirates be subclassified? Cancer Cytopathol. 2010; 118:
186–189.
88. Renshaw A.A. Significance of repeatedly nondiagnostic thyroid
fineneedle aspirations. Am. J. Clin. Pathol. 2011; 135: 750–752.
89. Richards M.L., Bohnenblust E., Sirinek K., Bingener J. Nondiagnostic thyroid fineneedle aspiration biopsies are no longer
a dilemma. Am. J. Surg. 2008; 196: 398–402.
90. Saggiorato E., De Pompa R., Volante M., Cappia S. et al. Characterization of thyroid ‘follicular neoplasms’ in fineneedle aspiration cytological specimens using a panel of immunohistochemical
markers: a proposal for clinical application. Endocrine-Related
Cancer 2005; 12: 305–317.
91. Sclabas G.M., Staerkel G.A., Shapiro S.E. et al. Fineneedle aspiration of the thyroid and correlation with histopathology in a contemporary series of 240 patients. Am. J. Surg. 2003; 186: 702–709.
92. Sebo T.J. What are the keys to successful thyroid FNA interpretation? Clin. Endocrinol. 2012; 77: 13–17.
93. Seningen J.L., Nassar A., Henry M.R. Correlation of Thyroid
Nodule FineNeedle Aspiration Cytology With Corresponding Histology at Mayo Clinic, 2001–2007: An Institutional Experience
of 1,945 Cases . Diagn. Cytopathol. 2012; 40: E27–E32.
94. Seong N. UltrasonographyGuided FineNeedle Aspiration of
Thyroid Incidentaloma: Correlation With Pathological Findings.
Clin. Endocrinol. 2004; 60: 145–147.
95. Sharma R., Mondal A., Shankar L.R. et al. Differentiation of
malignant and benign solitary thyroid nodules using 30-and
120minute tc99m MIBI scans. Clin. Nucl. Med. 2004; 29:
534–537.
96. Singh R.S., Wang H.H. Timing of Repeat Thyroid Fine-Needle
Aspiration in the Management of Thyroid Nodules. Acta
Cytologica 2011; 55: 544–548.
97. Smadi A.A., Ajarmeh K., Wreikat F. FineNeedle Aspiration of
Thyroid Nodules has high sensitivity and specificity. Rawal Med. J.
2008; 33: 221–224.
98. Somma J., Schlecht N.F., Fink D. et al. Thyroid fine needle aspiration cytology: follicular lesions and the gray zone. Acta Cytol.
2010; 54: 123–131.
99. Stephen S., Raab S. et al. Errors in Thyroid Gland Fine-Needle
Aspiration. Am. J. Clin. Pathol. 2006; 125: 873–882.
100.Theoharis C.G.A., Schofield K.M., Hammers L. et al. The Bethesda
Thyroid FineNeedle Aspiration Classification System: Year 1 at
an Academic Institution. Thyroid 2009; 19: 1215–1226.
101.Thyroid cancer – UK incidence statistics http://info.cancerresearchuk.org/cancerstats/types/thyroid/incidence/
102.Thyroid cancer – UK mortality statistics http://info.cancerresearchuk.org/cancerstats/types/thyroid/mortality/
103.Van der Laan P.A., Krane J.F., Cibas E.S. The Frequency of ‘Atypia
of Undetermined Significance’ Interpretations for Thyroid FineNeedle Aspirations Is Negatively Correlated with Histologically
Proven Malignant Outcomes. Acta Cytologica 2011; 55: 512–517.
104.Van der Laan P.A., Marqusee E., Krane J.F. Clinical outcome for
atypia of undetermined significance in thyroid fineneedle aspirations: should repeated FNA be the preferred initial approach? Am.
J. Clin. Pathol. 2011; 135: 770–775.
105.Van der Laan P.A., Renshaw A.A., Krane J.F. 2012 Atypia of undetermined significance and

The role of fineneedle aspiration biopsy in the dynamic monitoring of patients with nodular goiter

G. Semkina, V. Smirnova, F. Abdulhabirova, V. Vanushko

Review of the literature devoted to the relevance of fineneedle aspiration biopsy in the diagnosis of thyroid nodules. Application of the new classification system, the interpretation of FNA can significantly increase the reproducibility of the method and reduce the number of falsenegative results. This review summarizes recent data on the epidemiology of thyroid nodules, new system of the interpretation of FNA cytology findings, the role of FNA in the dynamic monitoring of benign tumors of thyroid gland.

Keywords:
nodular goiter, FNA, cytological evaluation

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