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Контраст индуцированная нефропатия (КИН), согласно рекомендациям Европейского общества уроради ологов (ЕОУР), определяется как ''острое нарушение по чечной функции вследствие введения йодированных контрастных средств (КС) при отсутствии других при чин''. Более правильно КИН следует определять как ''острое нарушение почечной функции, требующее времен ного или продолжительного применения диализа, всле дствие введения КС при отсутствии других причин''.
Ключевые слова:
контраст-индуцированная нефро	 патия, контрастные вещества
Литература:
1. Aspelin P, Aubry P, Fransson SG et al.: Nephrotoxic effects
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Acetylcysteine in the prevention of contrast	induced
nephropathy: a case study of the pitfalls in the evolution of
evidence. Arch.Intern.Med. 166:161	166, 2006.
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Induced Nephropathy in Patients With Chronic Kidney
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tions to ionic and nonionic contrast media. A report from
the Japanese Committee on the Safety of Contrast Media.
Radiology. 175:621	628, 1990.
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patients undergoing coronary procedures using iso	
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Obviate Worsening Nephropathy After Angioplasty In
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17. Mehran R, Nikolsky E: Contrast	induced nephropathy: efi	
nition, epidemiology, and patients at risk. Kidney
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induced nephrotoxicity: a consensus report. Contrast
Media Safety Committee, European Society of Urogenital
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a Continuous Quality Improvement Initiative With Practice
and Outcome Variations of Contemporary Percutaneous
Coronary Interventions. Circulation. : 2006.
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volume supplementation. Kidney Int.Suppl.S16	S19, 2006.
21. Newhouse JH, Kho D, Rao QA et al.: Frequency of serum
creatinine changes in the absence of iodinated contrast
material: implications for studies of contrast nephrotoxici	
ty. AJR Am.J.Roentgenol. 191:376	382, 2008.
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between visipaque (iodixanol) and hexabrix (ioxaglate) in cor	
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23. Rudnick MR, Davidson C, Laskey W et al.: Nephrotoxicity
of iodixanol versus ioversol in patients with chronic kidney
disease: the Visipaque Angiography/Interventions with
Laboratory Outcomes in Renal Insufficiency (VALOR) Trial.
Am.Heart J. 156:776	782, 2008.
24. Seeliger E, Flemming B, Wronski T et al.: Viscosity of con	
trast media perturbs renal hemodynamics.
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25. Sieber M, Jost G, Lengsfeld P, Seidensticker P: Influence
of the Viscosity and Osmolality of Iodinated Contrast
Agents on the Retention Time in the Kidney. (abstract)
J.Am.Soc.Nephrol. 18: 2007.
26. Solomon R, Barrett B: Follow	up of patients with contrast	
induced nephropathy. Kidney Int.Suppl.S46	S50, 2006
27. Solomon R, Deray G: How to prevent contrast	induced
nephropathy and manage risk patients: practical recom	
mendations. Kidney Int.Suppl.S51	S53, 2006.
28. Solomon RJ, Natarajan MK, Doucet S et al.: Cardiac
Angiography in Renally Impaired Patients (CARE) study: a
randomized double	blind trial of contrast	induced
nephropathy in patients with chronic kidney disease.
Circulation. 115:3189	3196, 2007.
Contrast induced nephropathy, according to recom mendations of European Society of Uroradiologists (ESU), is defined as an acute kidney's dysfunction resulting from injection of iodine contrast agents if any other reasons are absent. The more correct definition of contrast induced nephropathy is ''an acute kidney's dysfunction, requiring a short or long term hemodialysis''.
Keywords:
contrast-induced nephropathy, contrast agents